Have the attitudes on the use of hormone replacement tharapy been changed in women who have had breast cancer?

Abstract:

Hormone replacement therapy (HRC) is the only successful treatment for women with postmenopausal disorders. It is known that estrogen and progesterone can be tumor growth promoters, especially in breast cells, but it has not been proven that they cause breast cancer. Breat cancer is the most common neoplasm in women, especially between the ages of 40 and 60 years. For many years, oncologists have not recommended HRC for women who have had breast cancer, although studies confirm that in some patients the benefit from HRC administration may outweigh the risk of a new disease. On the other hand, a positive family history, especially in women with BRCA1/2 mutations, has a significant influence on breast cancer incidence. Thus, women with close relatives who had breast cancer should be careful in taking HRC and consider other, non-hormonal options for the prevention of postmenopausal disorders.

Key words:
breast neoplasms; hormone replacement therapy; recurrence